(aR,bR)-rel-6-Chloro-a-(2,4-difluorophenyl)-5-fluoro-b-methyl-a-(1H-1,2,4-triazol-1-ylmethyl)-4-pyrimidineethanol
Applications (αR,βR)-rel-6-Chloro-α-(2,4-difluorophenyl)-5-fluoro-β-methyl-α-(1H-1,2,4-triazol-1-ylmethyl)-4-pyrimidineethanol is an intermediate in synthesizing rel-(R,R)-Voriconazole (V759990), The (R,R)-enantiomer of Voriconazole. An antifungal (systemic). An ergosterol biosynthesis inhibitor.
References Sanati, H., et al.: Antimicrob. Ag. Chemother., 41, 2492 (1997)