The Case of Misoprostol and the WHO Model Essential Medicine List" examines how scientific evidence and social networks shape health policies. Specifically, it highlights the influence of advocacy groups, healthcare professionals, and policy makers on the inclusion of Misoprostol in the WHO Model Essential Medicines List. This case underscores the complex interaction between scientific data, political influence, and social networks in determining which medicines are prioritized for global health policies, reflecting both scientific advancements and the broader societal and economic factors that drive policy decisions.